Table of Contents
Clindapet (Clindamycin) is an antibiotic medication commonly used in veterinary medicine to treat bacterial infections in pets. It belongs to the lincosamide class of antibiotics and works by inhibiting the growth of bacteria and preventing their further spread.
What Is Clindapet (Clindamycin)?
Clindamycin is a new antibiotic generation, effective against a wide range of bacteria, including both gram-positive and some gram-negative bacteria. It is often used to treat infections of the skin, mouth, bone, and respiratory tract in dogs and cats. It can also be prescribed for certain dental infections, abscesses, and other soft tissue infections.
Mechanism of Action
Clindamycin exerts its antimicrobial effect by inhibiting bacterial protein synthesis. It binds to the 50S subunit of the bacterial ribosome, specifically to the 23S rRNA, a ribosomal RNA complex component. This binding prevents the formation of peptide bonds between amino acids and inhibits the elongation of the nascent peptide chain during protein synthesis. By interfering with protein synthesis, Clindamycin disrupts the bacterial cell’s ability to produce essential proteins necessary for their survival and growth. This ultimately leads to the inhibition of bacterial growth and the killing of susceptible bacteria.
The medicine is primarily active against anaerobic bacteria, including certain gram-positive and gram-negative anaerobes. It is also effective against some aerobic bacteria, such as streptococci, staphylococci, and pneumococci.
Forms of Clindamycin
How is Clindamycin supplied?
It is available in various forms for different routes of administration. Here are some common forms of Clindamycin.
Tablets/Capsules
It is commonly available for oral administration in Clindamycin tablets for dogs and cats or in capsule form. Clindamycin tablets for animals or capsules come in different strengths. Typically, you may find Clindamycin 75mg to 300 mg for dogs and cats. Although strengths may vary depending on the manufacturer. You may check Сlindamycin reviews and Clindamycin 300 mg price on the Internet and buy Clindamycin tablets.
Lotion
The lotion is a topical formulation for treating certain skin infections. It is typically applied directly to the affected area of the skin. Clindamycin oral liquid may be found in Australia.
Injection
The medicine can be administered intravenously (IV) or intramuscularly (IM) as an injection. Injectable Clindamycin is usually reserved for more severe infections or when oral administration is impossible.
Wipes
Clindamycin wipes are medicated wipes that contain Clindamycin as an active ingredient. These wipes are often used to treat certain skin conditions or infections.
It’s important to note that the availability of different forms of the medicine may vary depending on the country, brand, and specific veterinary formulations. Therefore, it is always recommended to consult a veterinarian or follow the prescribing information provided by the manufacturer for proper and appropriate use of Clindamycin in pets.
Ingredients
Let’s now check the Clindamycin tablets formulation.
Each uncoated tablet contains Clindamycin Hydrochloride IP equivalent to:
Clindamycin – 300mg
Excipients – q.s.
Clindamycin hydrochloride is a salt form of the antibiotic medication clindamycin. It is the hydrochloride salt of Clindamycin derived from the clindamycin base.
Clindamycin hydrochloride is a white crystalline powder that is soluble in water. It is used in various pharmaceutical formulations for oral and parenteral administration. In addition, the hydrochloride form of Clindamycin is often used to enhance the stability and solubility of the drug, making it suitable for different routes of administration.
Clindamycin hydrochloride has the exact mechanism of action and therapeutic properties as a clindamycin base.
Uses of Clindapet (Clindamycin)
Clindamycin tablets are used when bacterial infections are suspected or confirmed. Veterinarians typically prescribe it for pets in the following situations:
- Bacterial Infections: It is effective against a wide range of bacteria and may be prescribed for infections of the skin, soft tissues, respiratory tract, dental infections, and certain bone infections.
- Dental Infections: Clindapet is often used to treat dental infections in pets, such as periodontal disease, abscesses, or other oral infections. It may be prescribed with other treatments or as a standalone therapy.
- Surgical Prophylaxis: In some cases, Clindamycin may be prescribed as a preventive measure to reduce the risk of infection after specific surgical procedures. Depending on the specific situation and the veterinarian’s recommendation, it may be used before and/or after surgery.
- Other Infections: Depending on the specific circumstances, Clindapet may treat other pet infections.
It’s crucial to note that using the best antibiotic Clindamycin, should be based on the specific needs and diagnosis of the pet. The decision to use Clindamycin or any other antibiotic should be made by a veterinarian, who can adequately evaluate the pet’s condition and prescribe the appropriate treatment.
Clindamycin for Dogs
As mentioned, Clindamycin is commonly used in dogs to treat various bacterial infections, like skin and soft tissue infections, dental infections, respiratory tract infections, bone infections, and other types of bacterial infections.
People ask: how much Clindamycin should I give my dog? The dosage and Clindamycin’s long-term use will depend on the specific condition, the dog’s weight and size, and the veterinarian’s recommendation.
Clindamycin for Cats
The medicine is also used in cats to treat the same bacterial infections. Therefore, it can be prescribed for similar conditions as in dogs.
How much is Clindamycin for cats? Cats may require different dosing than dogs, and it’s essential to strictly follow the veterinarian’s instructions for the safe and effective use of Clindamycin in cats.
In both cases, it’s crucial to consult a veterinarian for an accurate diagnosis and proper prescription of the medicine or any other medication for your pet. The veterinarian will consider your dog or cat’s specific needs and conditions to determine the appropriate dosage, duration, and administration instructions for Clindapet.
How and How Long Can Clindamycin Be Used for Animals?
The duration of Clindapet treatment for animals can vary depending on the specific condition being treated, the type and location of the infection, the severity of the infection, the animal’s overall health, and the individual response of the animal. Typically, the duration of clindamycin therapy ranges from a few days to several weeks.
In most cases, it is crucial to complete the entire course of treatment as the veterinarian prescribes, even if the symptoms improve or disappear before the treatment is completed. This is because prematurely stopping antibiotic treatment can allow bacteria to survive and potentially develop Clindamycin resistance.
Administering the Tablets
The Clindamycin dosage for dogs and cats and administration of clindamycin hydrochloride depends on the specific condition being treated, the weight and species of the animal, and the veterinarian’s recommendation.
There is no exact information about how to take it because the dosage varies in every specific case. However, here are some general guidelines for administering clindamycin tablets (300 mg) to cats and dogs:
- Follow Veterinarian’s Instructions: ensure you clearly understand the veterinarian’s instructions regarding the dosage, frequency, and duration of clindamycin treatment for your cat or dog.
- Administer with or without food: the medicine can generally be given with or without food, depending on the veterinarian’s recommendation. Some pets tolerate it better when given with a small amount of food to help prevent stomach upset. However, follow the specific instructions provided by your veterinarian.
- Crushing or Splitting Tablets: if necessary, you may need to crush or split the clindamycin tablets to achieve the appropriate dosage for your pet. Can Clindamycin tablets be chewed, or can you crush Clindamycin tablets? Yes, you can, but it is essential to consult your veterinarian before altering the tablet form, as some medications have extended-release properties that can be affected by crushing or splitting.
- Use Pill Pockets or Hide in Food: if your pet is reluctant to take the tablet directly, you can try using pill pockets (commercially available treats designed to hold medication) or hiding the crushed tablet in a small amount of their regular food. Ensure that your pet consumes the entire dose for the full therapeutic effect.
- Follow the Full Course of Treatment: complete the entire prescribed course of clindamycin treatment, even if your pet’s symptoms improve, before finishing the medication.
As with any medication, it is recommended to consult a veterinarian for accurate and specific information about using clindamycin hydrochloride in pets.
Important Safety Information for Owners
It’s important to note that Clindamycin is not effective against all types of bacteria, and its use should be based on the susceptibility of the specific bacteria causing the infection. Additionally, overuse or misuse of antibiotics like Clindamycin can contribute to the development of antibiotic resistance, so it should only be used when necessary and under the guidance of a veterinarian.
Is Clindamycin safe in pregnancy?
Clindamycin should be used cautiously in pets while they are pregnant or lactating animals, as its safety during these periods has not been extensively studied. Your veterinarian will assess the risks and benefits before prescribing Clindapet in such cases.
If you have specific questions or concerns about Clindamycin or any other medication for your pet, we recommend consulting a veterinarian for the most accurate and up-to-date information.
Veterinary Prescription
Like any medication, Clindapet should be used under the guidance of a veterinarian. Only a veterinarian can evaluate your pet’s overall health and prescribe this medicine, the dosage, and the duration of treatment. Follow all the instructions and complete the entire course of treatment to ensure effective results and minimize the risk of antibiotic resistance.
Contraindications
Who should not take Clindamycin?
The medicine can interact with certain medications, including other antibiotics or medications metabolized by the liver. Inform your veterinarian about all medications, supplements, or herbal products your pet is currently taking to avoid any potential drug interactions. So, what can you mix Clindamycin with, and what can you not mix with Clindamycin?
Some interactions include:
- Erythromycin: concurrent use of Clindamycin with erythromycin, another antibiotic in the macrolide class, may increase the risk of adverse effects.
- Neuromuscular Blocking Agents: Clindapet can enhance the effects of neuromuscular blocking agents used during anesthesia. This can lead to prolonged muscle relaxation and respiratory depression.
- Antidiarrheal Medications: medications used to treat diarrhea, such as kaolin-pectin and adsorbent antidiarrheal drugs, may reduce the absorption of Clindamycin and decrease its effectiveness.
- Medications Metabolized by the Liver: Clindapet can affect the metabolism of certain medications in the liver. Examples include anticonvulsants (such as phenobarbital), oral anticoagulants (such as warfarin), and some benzodiazepines.
- Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Clindamycin can interact with NSAIDs, commonly used to manage pain and inflammation. This interaction may increase the risk of gastrointestinal side effects, such as stomach ulcers or bleeding.
It’s important to note that this is not a complete list of all possible drug interactions. Different interactions may occur depending on the specific medications involved.
Side Effects
While Clindamycin is generally considered safe and effective when used as directed by a veterinarian, there are some warning information and precautions to be aware of. Check the table below:
| 1. Clindamycin allergic reaction | Some animals may be hypersensitive or allergic to Clindamycin or other antibiotics. It’s essential to inform your veterinarian if your pet has a history of medication allergies or adverse reactions. |
| 2. Gastrointestinal Upset | Clindapet can sometimes cause gastrointestinal side effects in animals, such as vomiting, diarrhea, or loss of appetite. If these symptoms occur, contact your veterinarian for guidance. |
| 3. Pseudomembranous Colitis | In rare cases, Clindamycin can lead to a severe condition called pseudomembranous colitis, characterized by severe diarrhea, abdominal pain, and potentially life-threatening complications. Contact your veterinarian immediately if your pet experiences persistent or severe diarrhea during or after clindamycin treatment. |
| 4. Overgrowth of Resistant Bacteria | Prolonged or inappropriate use of Clindamycin can lead to the overgrowth of bacteria resistant to the medication. This can result in the need for alternative antibiotics and may complicate future treatments. |
Contact your veterinarian if you notice these or any other Clindamycin side effects in dogs and cats.
Overdose and a Maximum Daily Dose
The Clindamycin oral maximum dose and the risk of overdose depend on factors such as the specific condition being treated, the weight of the animal, and the veterinarian’s recommendation.
In cases of accidental overdose, it is crucial to seek veterinary attention immediately. Overdose symptoms may include severe gastrointestinal upset (vomiting, diarrhea), neurological symptoms (such as seizures), or other signs of medication toxicity. Contacting a veterinarian or an emergency veterinary clinic is the best action in such situations.
Storage
Store Clindapet at room temperature, between 20°C and 25°C (68°F and 77°F). Avoid exposing it to extreme temperatures, direct sunlight, or excessive heat or cold. Do not freeze Clindamycin unless specifically instructed to do so. Please keep it dry, away from excess moisture and humidity. Store the medicine in a secure location, out of the reach of children and pets. Always check the shelf life of clindamycin tablets (Expiry Date). Do not use Clindamycin tablets if they are discontinued.
Generic and Brand Names of Clindapet (Clindamycin)
So, what is the generic for Clindamycin?
Clindamycin for pets is primarily available as generic formulations, although some brand names may also be associated with these generic formulations. Here are the generic and brand Clindamycin tablet names for pets:
Generic Names:
- Clindamycin
- Clindamycin hydrochloride
Brand Names:
- Clindapet is the best Clindamicyn brand.
- Antirobe (for dogs and cats) is a commonly used brand name for Clindamycin in veterinary medicine.
- Clevet for pets.
It’s important to note that the availability of specific brands may vary depending on your location and the prescribing practices in your country. Additionally, some veterinarians may use compounded formulations or prepare the medication in-house, which may not have a specific brand name.
Other Drugs in the Same Class
The Clindamycin antibiotic group is lincosamides. Lincomycin is another lincosamide antibiotic that works similarly to Clindamycin. It is used to treat certain bacterial infections in both humans and animals.
It’s important to note that while lincosamides are a specific class of antibiotics, Clindamycin is this class’s most commonly used and well-known member. Lincomycin, on the other hand, is less commonly prescribed.
Benefits of Using Clindamycin
What are the benefits of Clindamycin?
Clindamycin offers several benefits when used appropriately for the treatment of bacterial infections. Some of the benefits of using this remedy include:
- Effective against a wide range of bacteria: it is active against many Gram-positive bacteria, including Staphylococcus, Streptococcus, and certain anaerobic bacteria.
- Anaerobic coverage: Clindapet has excellent activity against anaerobic bacteria, which can survive and grow without oxygen.
- Alternative to Penicillin for individuals who are allergic to Penicillin or have a resistant infection. It can be effective in cases where other antibiotics may not be suitable or effective.
- Availability in Multiple Forms
FAQ
Can You Give 2 Clindamycin at Once?
No, giving two doses of Clindamycin without medical guidance is not recommended. Do not exceed Clindamycin’s recommended dosage.
Can You Give Clindapet for 10 Days?
The duration of treatment should be determined by a veterinarian based on the specific condition being treated. Typically, the duration of clindamycin therapy ranges from a few days to several weeks.
Does the Medicine Cause Yeast Infections?
Clindamycin can disrupt the normal balance of bacteria, potentially leading to yeast infections.
Do Clindamycin Pills Expire and How Long Do They Last Before They Еxpire?
Clindamycin pills expire; it is vital to use them before they expire. The expiration date can vary, so check the packaging for the specific timeframe.
How Fast Does Oral Clindapet Work?
The onset of action of oral Clindapet can vary, but it typically starts working within a few hours to a few days.
How Long Does It Take for Clindamycin to Absorb?
It is generally absorbed well after oral administration, but the absorption time can vary.
How Long Does It Take for Medicine to Dissolve?
The time it takes for the medicine to dissolve can vary depending on factors such as the specific formulation and individual physiology.
How Much Clindamycin Can You Take at Once?
A veterinarian should determine the medicine dosage based on the treatment’s specific condition.
Is Clindapet Dangerous to Take?
When appropriately used under veterinary guidance, it is generally safe. However, side effects can occur and should be monitored.
Is Clindamycin Hydrochloride the Same as Clindamycin?
Clindamycin hydrochloride is a specific salt form of Clindamycin and is considered the same medication with slight chemical variations.
When Should I Stop Giving My Pet Clindapet?
The duration of treatment should be determined by a veterinarian based on the specific condition being treated. Stop giving it if you notice any side effects when Clindamycin tablets for cats and dogs go bad, and contact a veterinarian.
Where Is Clindamycin Absorbed?
Clindamycin is primarily absorbed in the gastrointestinal tract after oral administration.
Why Is Oral Clindamycin Dose Lower Than IV?
The oral dose of Clindamycin is often lower than the intravenous (IV) dose (for example, Clindamycin 600 mg iv) due to differences in bioavailability and the route of administration.
Dr. Michael Boley is a veterinarian and the owner of two veterinary clinics, The Animal Doctor at Paris, and The Animal Doctor of Selmer Hospitals.